18 nights Argentina, Uruguay, Brazil, Spain

the capital city and chief port of Argentina, in the eastern central part of the country, on the Plata River; population 3,042,600 (est. 2008).

Montevideo is the capital and largest city of Uruguay. According to the 2011 census, the city proper has a population of 1,319,108 (about one-third of the country's total population) in an area of 201 square kilometres (78 sq mi). The southernmost capital city in the Americas, Montevideo is situated on the southern coast of the country, on the northeastern bank of the Río de la Plata.

The city was established in 1724 by a Spanish soldier, Bruno Mauricio de Zabala, as a strategic move amidst the Spanish-Portuguese dispute over the platine region. It was also under brief British rule in 1807. Montevideo is the seat of the administrative headquarters of Mercosur and ALADI, Latin America’s leading trade blocs, a position that entailed comparisons to the role of Brussels in Europe.

Rio de Janeiro is the second-most populous municipality in Brazil and the sixth-most populous in the Americas. The metropolis is anchor to the Rio de Janeiro metropolitan area, the second-most populous metropolitan area in Brazil and sixth-most populous in the Americas. Rio de Janeiro is the capital of the state of Rio de Janeiro, Brazil's third-most populous state. Part of the city has been designated as a World Heritage Site, named "Rio de Janeiro: CariocaLandscapes between the Mountain and the Sea", by UNESCO on 1 July 2012 as a Cultural Landscape.

Founded in 1565 by the Portuguese, the city was initially the seat of the Captaincy of Rio de Janeiro, a domain of the Portuguese Empire. Later, in 1763, it became the capital of the State of Brazil, a state of the Portuguese Empire. In 1808, when the Portuguese Royal Court transferred itself from Portugal to Brazil, Rio de Janeiro became the chosen seat of the court of Queen Maria I of Portugal, who subsequently, in 1815, under the leadership of her son, the Prince Regent, and future King João VI of Portugal, raised Brazil to the dignity of a kingdom, within the United Kingdom of Portugal, Brazil, and Algarves. Rio stayed the capital of the pluricontinental Lusitanian monarchy until 1822, when the War of Brazilian Independence began. This is one of the few instances in history that the capital of a colonising country officially shifted to a city in one of its colonies. Rio de Janeiro subsequently served as the capital of the independent monarchy, the Empire of Brazil, until 1889, and then the capital of a republican Brazil until 1960 when the capital was transferred to Brasília.

Alicante, or Alacant , both the Spanish and Valencian being official names, is a city and port in Spain on the Costa Blanca, the capital of the province of Alicante and of the comarca of Alacantí, in the south of the Valencian Community. It is also a historic Mediterranean port. The population of the city of Alicante proper was 330,525, estimated as of 2016, ranking as the second-largest Valencian city. Including nearby municipalities, the Alicante conurbation had 452,462 residents. The population of the metropolitan area (including Elche and satellite towns) was 757,085 as of 2014 estimates, ranking as the eighth-largest metropolitan area of Spain.